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Ultra-Fast-Acting Insulin Analogues: Unmet Needs and Rationale

This course addresses how postprandial glucose (PPG) levels affect overall hyperglycaemia and reviews the recommended target levels for PPG. The rationale for developing ultra-fast-acting insulin analogues is introduced, and guidance is provided to help you understand the time-action profiles of regular, fast-acting and ultra-fast-acting insulin analogues.

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  • Baseline assessment

    Baseline assessment

    Please answer the baseline assessment questions in order to start this course.

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  • Webcast

    Ultra-Fast-Acting Insulin Analogues – Unmet Needs and Rationale

    In this webcast, Professor Mathieu explains the rationale behind the need for ultra-fast-acting insulin analogues. The focus is on therapeutic insulin versus physiological insulin, and compares time–action profiles of regular-acting, fast-acting, and ultra-fast-acting insulin analogues.

    Upon completion of this activity, health care professionals should be able to:

    • Be aware of the differences between therapeutic insulin vs. physiological insulin
    • Understand the limitations of regular insulin analogues for insulin pumps
    • Know what ultra-fast-acting insulin analogues are
    • Be able to compare time-action profiles of regular, fast-acting and ultra-fast-acting insulin analogues
    • Be aware of which ultra-fast-acting insulin analogues are in development
    • Understand the convenience of ultra-fast-acting insulin analogues and the remaining challenges
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  • Infographic

    Postprandial Hyperglycaemia

    In this infographic, Professor Colagiuri considers the importance of controlling postprandial glucose levels in patients with diabetes, reviewing the current recommended target levels for postprandial glucose and discussing the therapeutic options (with a focus on ultra-rapid acting insulin analogues) that may help to reduce postprandial glucose levels in patients with diabetes.

    Learning objectives

    Upon completion of this activity, participants should be able to:                

    • Explain how postprandial glucose levels contribute to overall hyperglycaemia
    • List the recommended postprandial glucose levels for patients with diabetes
    • Recognize the potential of ultra-fast-acting insulin analogues in controlling postprandial glucose levels
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  • Selected article

    Moving toward the ideal insulin for insulin pumps

    In this activity you will be introduced to three recently published articles specially curated for this course by Professor Mathieu. These publications will educate you on the development of ultra-fast-acting insulins for use with insulin pumps, and on the pharmacokinetic/pharmacodynamic properties of two novel approaches: inhaled insulin and ultra-fast-acting insulin analogues.

    Learning objectives

    Following completion of this activity you should be able to:

    • Recognize that ultra-fast-acting insulin analogues provide a rapid onset of action that more closely mimics post-meal insulin release in healthy individuals
    • Describe the difference between fast-acting and ultra-fast-acting insulins, and characterize their pharmacokinetic/pharmacodynamic profiles
    • List the differences between inhaled insulin and subcutaneously administered insulin
    This course requires you to login. Don't have an account yet? Please register.
  • Selected article

    Pharmacokinetic and pharmacodynamic properties of a novel inhaled insulin

    In this activity you will be introduced to three recently published articles specially curated for this course by Professor Mathieu. These publications will educate you on the development of ultra-fast-acting insulins for use with insulin pumps, and on the pharmacokinetic/pharmacodynamic properties of two novel approaches: inhaled insulin and ultra-fast-acting insulin analogues.

    Learning objectives

    Following completion of this activity you should be able to:

    • Recognize that ultra-fast-acting insulin analogues provide a rapid onset of action that more closely mimics post-meal insulin release in healthy individuals
    • Describe the difference between fast-acting and ultra-fast-acting insulins, and characterize their pharmacokinetic/pharmacodynamic profiles
    • List the differences between inhaled insulin and subcutaneously administered insulin
    This course requires you to login. Don't have an account yet? Please register.
  • Selected article

    Faster-acting insulin aspart: earlier onset of appearance and greater early pharmacokinetic and pharmacodynamic effects than insulin aspart

    In this activity you will be introduced to three recently published articles specially curated for this course by Professor Mathieu. These publications will educate you on the development of ultra-fast-acting insulins for use with insulin pumps, and on the pharmacokinetic/pharmacodynamic properties of two novel approaches: inhaled insulin and ultra-fast-acting insulin analogues.

    Learning objectives

    Following completion of this activity you should be able to:

    • Recognize that ultra-fast-acting insulin analogues provide a rapid onset of action that more closely mimics post-meal insulin release in healthy individuals
    • Describe the difference between fast-acting and ultra-fast-acting insulins, and characterize their pharmacokinetic/pharmacodynamic profiles
    • List the differences between inhaled insulin and subcutaneously administered insulin
    This course requires you to login. Don't have an account yet? Please register.
  • Final assessment

    Please answer the final assessment questions in order to complete this part of the course.

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  • UEMS accreditation test

    Please remember the following points while taking this test:

    • The assessment consists of 10 questions
    • You need to score a minimum of 80% to pass the assessment
    • Read the question carefully, select an option provided below the question, and then click the “Submit” button
    • You cannot change the answer once you have clicked the “Submit” button
    • If you exit the assessment before completing all the questions, you will have to attempt it again from the beginning.

    Validity of accreditation: 2 years after date of accreditation by: UEMS-EACCME

    >> Click Start when you are ready to take the assessment

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  • e-Learning Material Evaluation

    Ultra-Fast-Acting Insulin Analogues: Unmet Needs and Rationale

    The aim of this evaluation process is to maintain high educational standards and provide a reference for continuous improvement.

    In order to receive your certificate please complete this survey.

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